A Clinical Feasibility Study of Spinal Evoked Compound Action Potential Estimation Methods
Krishnan Chakravarthy, James J. FitzGerald, Andrew Will, Karen Trutnau, Robert M. Corey, David Dinsmoor, Leonid M. Litvak
Abstract
OBJECTIVES: |). MATERIALS AND METHODS: parameters following the fit. RESULTS: |) on the ECAP estimate was superior (p < 0.05) with the HP and AM schemes relative to the others. CONCLUSIONS: This work represents the first comprehensive assessment of spinal ECAP estimation schemes. Understanding the clinically relevant sensitivities of these schemes is increasingly important, particularly with closed-loop SCS systems using ECAP as a feedback control variable where misclassification of artifact as neural signal may lead to suboptimal therapy adjustments.
Topics & Concepts
Artifact (error)Compound muscle action potentialEvoked potentialSIGNAL (programming language)StimulationFilter (signal processing)Computer scienceSensitivity (control systems)Exponential functionSpinal cordBiomedical engineeringElectrophysiologyMathematicsMedicineArtificial intelligenceAudiologyInternal medicineElectronic engineeringMathematical analysisEngineeringProgramming languagePsychiatryComputer visionPain Management and TreatmentMusculoskeletal pain and rehabilitationTranscranial Magnetic Stimulation Studies