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Review of the current state of protein aggregation inhibition from a materials chemistry perspective: special focus on polymeric materials

Robin Rajan, Sana Ahmed, Neha Sharma, Nishant Kumar, Alisha Debas, Kazuaki Matsumura

2021Materials Advances186 citationsDOIOpen Access PDF

Abstract

This review discusses various aspects of protein aggregation and inhibition strategies, emphasizing the use of polymers, which is one of the most promising approaches to combat various aggregation-induced complications in neurodegenerative diseases and protein therapeutics.

Topics & Concepts

Perspective (graphical)Focus (optics)Protein aggregationNanotechnologyChemistryCurrent (fluid)NeuroscienceBiophysicsComputer scienceMaterials scienceBiochemistryEngineeringBiologyPhysicsArtificial intelligenceOpticsElectrical engineeringbiodegradable polymer synthesis and propertiesNanoparticle-Based Drug DeliveryGraphene and Nanomaterials Applications