Recent Advancement in H<sub>8</sub>–BINOL Catalyzed Asymmetric Methodologies
Rajpratap Kshatriya
Abstract
High Resolution Image Download MS PowerPoint Slide H 8 –BINOL, a partially reduced form of BINOL, is widely employed in a broad array of organocatalyzed asymmetric methodologies. Over the last 25 years, asymmetric organocatalysis has witnessed an incredible improvement, and an advancement still continues to get a single enantio-enriched product. The broad-spectrum applications of H 8 –BINOL organocatalyst in C–C bond formation, C-heteroatom bond construction, name reactions, pericyclic reactions, and one pot and multicomponent reaction are attracting the attention of researchers. A diversified unique H 8 –BINOL-based catalyst has been synthesized and screened for catalytic activity. In this Review we frame out the H 8 –BINOL catalyzed novel discoveries from the last two decades.