Antigen/HLA-agnostic strategies for Characterizing Tumor-responsive T cell receptors in PDAC patients via single-cell sequencing and autologous organoid application
Xu Wang, Zhengjie Dai, Xuan Lin, Xuan Zou, Ruijie Wang, Yesboli Tasiheng, Yu Yan, Mingjian Ma, Yusheng Chen, Cheng He, Chen Liu, Xianjun Yu
Topics & Concepts
T-cell receptorBiologyKRAST cellCancer researchOrganoidPeripheral blood mononuclear cellTumor-infiltrating lymphocytesCellAntigenImmunologyCell biologyCancerImmune systemCD8In vitroGeneticsColorectal cancerCAR-T cell therapy researchCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction