Intestinal iron bio-accessibility changes by Lignin and the subsequent impact on cell metabolism and intestinal microbiome communities
Richard D. Horniblow, Prachi Pathak, Maryam Eshrati, Gladys O. Latunde‐Dada, Chris Tselepis
Abstract
decreased which could be attributed to the changes in iron bio-accessibility due to iron chelation. In summary, we demonstrate that lignin is an effective luminal iron chelator. Iron chelation leads to the limitation of intracellular iron import whilst, despite increasing iron solubility, favouring the growth of beneficial bacteria.
Topics & Concepts
EnterocyteLigninMetabolismGut microbiomeMicrobial metabolismMicrobiomeMicrobiologyBacteriaChemistryBiochemistryBiologyGut floraBioinformaticsSmall intestineBotanyGeneticsGut microbiota and health