Osteopontin associates with brain TRM-cell transcriptome and compartmentalization in donors with and without multiple sclerosis
Cheng‐Chih Hsiao, Hendrik J. Engelenburg, Aldo Jongejan, Jing Zhu, Baohong Zhang, Michaël Mingueneau, Perry D. Moerland, Inge Huitinga, Joost Smolders, Jörg Hamann
Abstract
cells and reveals their tight control in MS lesions.
Topics & Concepts
OsteopontinMicrogliaBiologyTranscriptomeMultiple sclerosisCD8White matterT cellParenchymaPhenotypePathologyCell biologyMolecular biologyInflammationImmunologyGene expressionImmune systemGeneMedicineGeneticsRadiologyMagnetic resonance imagingNeuroinflammation and Neurodegeneration MechanismsT-cell and B-cell ImmunologyBone and Dental Protein Studies