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Design and synthesis of ibuprofen-quinoline conjugates as potential anti-inflammatory and analgesic drug candidates

Amany M. Ghanim, Adel S. Girgis, Benson M. Kariuki, Nermin Samir, Mona F. Said, Anwar Abdelnaser, Soad M. Nasr, Mohamed S. Bekheit, Mohamed F. Abdelhameed, Ahmad J. Almalki, Tarek S. Ibrahim, Siva S. Panda

2021Bioorganic Chemistry73 citationsDOI

Topics & Concepts

IbuprofenChemistryIn vivoAnalgesicNitric oxideQuinolinePharmacologyCarrageenanConjugateAnti-inflammatoryNitric oxide synthaseBiochemistryOrganic chemistryMedicineMathematicsBiologyMathematical analysisBiotechnologyInflammatory mediators and NSAID effectsBioactive Compounds and Antitumor AgentsOrganic Chemistry Cycloaddition Reactions
Design and synthesis of ibuprofen-quinoline conjugates as potential anti-inflammatory and analgesic drug candidates | Litcius