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Viruses as vectors for the delivery of gene-editing reagents

Evan E. Ellison, James C. Chamness, Daniel F. Voytas

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Abstract

Introduction 2 DNA viruses: replicon vectors for efficient gene editing through homology-directed repair (HDR) 3 Geminiviral replicons (GVRs): deconstructed geminiviruses that serve as replicating vectors in plants 4 Replicon vectors for efficient homology-directed repair 5 Case studies: GVR-based editing strategies in dicots and monocots 6 GVR-based editing strategies: summary and future trends 7 RNA viruses: mobile vectors broadly applicable for gene-editing reagent delivery 8 Case studies: use viral vectors to create permanent genetic changes 9 RNA viral vectors: conclusion and future trends 10 Where to look for further information

Topics & Concepts

Gene deliveryComputational biologyGenome editingBiologyGeneComputer scienceVector (molecular biology)GeneticsCRISPRVirologyGenetic enhancementRecombinant DNAPlant Virus Research StudiesCRISPR and Genetic EngineeringPlant and Fungal Interactions Research
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