Vascular disrupting agent-induced amplification of tumor targeting and prodrug activation boosts anti-tumor efficacy
Sheng Hong, Qian‐Xiao Huang, Ping Ji, Xuan Pang, Yunxia Sun, Si‐Xue Cheng, Xian‐Zheng Zhang, Xuesi Chen
Topics & Concepts
ProdrugTirapazamineNanocarriersTumor hypoxiaHypoxia (environmental)Cancer researchTumor microenvironmentChemotherapyChemistryPharmacologyMedicineDrugInternal medicineIn vitroTumor cellsRadiation therapyBiochemistryCytotoxicityOxygenOrganic chemistryNanoplatforms for cancer theranosticsCancer, Hypoxia, and MetabolismNanoparticle-Based Drug Delivery