Cellular irinotecan resistance in colorectal cancer and overcoming irinotecan refractoriness through various combination trials including DNA methyltransferase inhibitors: a review
Shogo Ozawa, Toshitaka Miura, Jun Terashima, Wataru Habano
Abstract
Cancer Drug Resistance is an open access journal, focusing on pharmacological aspects of drug resistance and its reversal, molecular mechanisms of drug resistance and drug classes, etc. Both clinical and experimental aspects of drug resistance in cancer are included.
Topics & Concepts
IrinotecanCetuximabColorectal cancerCancer researchCamptothecinMedicinePharmacologyDrug resistanceAbcg2Topoisomerase inhibitorTopoisomeraseInternal medicineBiologyCancerOncologyATP-binding cassette transporterGeneticsTransporterGeneBiochemistryDNACancer therapeutics and mechanismsColorectal Cancer Treatments and StudiesCholangiocarcinoma and Gallbladder Cancer Studies