Voltage-Gated Calcium Channels
Gerald W. Zamponi, Norbert Weiss
Abstract
The article concentrates on representatives of voltage-gated calcium ion-channels that are present in practically all cells. Considered are the activation and inactivation processes of calcium channels and their molecular mechanisms. The review represents modem classification of voltage-gated calcium channels, draws parallels with the earlier classifications and discusses calcium currents going through various calcium channels. Presented are the genetic, molecular-biological, bio-physical, physiological and pharmacological information for each type of the ten known voltage-gated calcium channels.
Topics & Concepts
Voltage-dependent calcium channelVoltage-gated ion channelCalcium channelCalciumIon channelChemistryR-type calcium channelN-type calcium channelBiophysicsT-type calcium channelProtein subunitBiologyBiochemistryReceptorOrganic chemistryGeneIon channel regulation and functionNeuroscience and Neural EngineeringElectrochemical Analysis and Applications