Electrochemically Enabled Selenium Catalytic Synthesis of 2,1-Benzoxazoles from <i>o</i>-Nitrophenylacetylenes
Lin‐Wei Wang, Yufeng Feng, Hong-Min Lin, Haitao Tang, Ying‐Ming Pan
Abstract
The study reported an electrochemically mediated method for the preparation of 2,1-benzoxazoles from o-nitrophenylacetylenes. Different from the traditional electrochemical reduction of nitro to nitroso, the nitro group directly underwent a cyclization reaction with the alkyne activated by selenium cation generated by the anodic oxidation of diphenyl diselenide and finally produced the desired products.
Topics & Concepts
DiselenideDiphenyl diselenideSeleniumNitroAlkyneElectrochemistryNitrosoCatalysisChemistryAnodic oxidationCombinatorial chemistryInorganic chemistryMedicinal chemistryOrganic chemistryElectrodePhysical chemistryAlkylSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsSynthesis of Indole Derivatives