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KaryoCreate: A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Nazario Bosco, Aleah Goldberg, Xin Zhao, Joseph C. Mays, Pan Cheng, Adam F. Johnson, Joy J. Bianchi, Cecilia Toscani, Elena Di Tommaso, Lizabeth Katsnelson, Dania Annuar, Sally Mei, Roni E. Faitelson, Ilan Y. Pesselev, Kareem S. Mohamed, Angela Mermerian, Elaine M Camacho-Hernandez, Courtney A. Gionco, Julie Manikas, Yi-Shuan Tseng, Zhengxi Sun, Somayeh Fani, Sarah Keegan, Scott M. Lippman, David Fenyö, Simona Giunta, Stefano Santaguida, Teresa Davoli

2023Cell70 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCRISPRCentromereAneuploidyGeneticsChromosomeComputational biologyGeneChromosomal and Genetic VariationsCRISPR and Genetic EngineeringGenomic variations and chromosomal abnormalities
KaryoCreate: A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres | Litcius