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Analysis and Optimal Control of a Fractional Order SEIR Epidemic Model With General Incidence and Vaccination

Sara Soulaimani, Abdelilah Kaddar

2023IEEE Access28 citationsDOIOpen Access PDF

Abstract

In this article, we present an analysis and optimal control investigation of a fractional order SEIR epidemic model with General Incidence and Vaccination. We utilize fractional calculus to account for memory effects and non-local interactions in the disease transmission process. Our analysis focuses on investigating the existence, uniqueness and stability of equilibrium points, while considering the impact of vaccination on the disease dynamics. Additionally, we develop an optimal control strategy to minimize the number of infected individuals over a given time horizon by optimizing the vaccination rate. Numerical simulations are performed to validate the theoretical results and demonstrate the effectiveness of the proposed optimal control strategy in mitigating the spread of the epidemic. The findings of this study contribute to a better understanding of the dynamics of fractional order SEIR epidemic models and provide insights into the design of efficient control measures for infectious diseases.

Topics & Concepts

Epidemic modelOptimal controlUniquenessVaccinationComputer scienceMathematical optimizationStability (learning theory)Mathematical modelling of infectious diseaseTransmission (telecommunications)MathematicsInfectious disease (medical specialty)DiseaseMedicinePopulationMachine learningVirologyEnvironmental healthMathematical analysisTelecommunicationsPathologyMathematical and Theoretical Epidemiology and Ecology ModelsFractional Differential Equations SolutionsEvolution and Genetic Dynamics