Colorimetric analysis of extracellular vesicle surface proteins based on controlled growth of Au aptasensors
Xiaojie Wang, Xinxin Yuan, Kexin Fu, Chang Liu, Lu Bai, Xinchao Wang, Xiaoyue Tan, Yuying Zhang
Abstract
A sensitive, simple, rapid and wash-free colorimetric assay for detection of surface proteins in extracellular vesicles is presented, with a limit of detection down to 0.7 ng μL<sup>−1</sup> against MCF-7 cell-derived extracellular vesicles.
Topics & Concepts
Extracellular vesiclesVesicleExtracellularChemistryDetection limitExtracellular vesicleChromatographyBiophysicsBiochemistryCell biologyBiologyMicrovesiclesMembranemicroRNAGeneExtracellular vesicles in diseaseAdvanced biosensing and bioanalysis techniquesAdvanced Nanomaterials in Catalysis