STING upregulation mediates ferroptosis and inflammatory response in lupus nephritis by upregulating TBK1 and activating NF-κB signal pathway
Jinshu Chen, P. S. Chen, Yijin Song, Jiaxin Wei, Fan Wu, Jing Sun, Zhiquan Xu
Topics & Concepts
Downregulation and upregulationNF-κBStingTANK-binding kinase 1Signal transductionSignal pathwayLupus nephritisNFKB1InflammationCancer researchChemistryCell biologyMedicineImmunologyBiologyInternal medicineMAPK/ERK pathwayGeneTranscription factorMAP kinase kinase kinaseBiochemistryEngineeringAerospace engineeringDiseaseinterferon and immune responsesCancer-related molecular mechanisms researchRNA modifications and cancer