Organocatalytic Dynamic Kinetic Resolution: An Update
Hélène Pellissier
Abstract
Abstract It is only in the two last decades that the first examples of organocatalytic dynamic kinetic resolutions (DKRs) have been disclosed. These methodologies allow resolving racemic compounds with up to quantitative yield. Today, a variety of chiral organocatalysts are capable of providing excellent enantioselectivities in many types of transformations evolving through DKR. The goal of this review is to update the field of organocatalytic DKRs since 2016. It is divided into six sections, according to the different types of organocatalysts employed in these reactions, such as Brønsted acid catalysts, hydrogen‐bonding catalysts, N‐heterocyclic carbene catalysts, Lewis base catalysts, phase‐transfer catalysts, and cinchona alkaloid‐based Brønsted base catalysts.