Recent advances in N-heterocyclic carbene (NHC)-catalyzed fluorination and fluoroalkylation
Zefeng Jin, Fangfang Zhang, Xiao Xiao, Nengzhong Wang, Xin Lv, Liejin Zhou
Abstract
Organofluorine compounds are of high value. NHC-catalyzed fluorination and fluoroalkylation have served as powerful and versatile vehicles for accessing the related organofluorines. This review focuses on the recent developments in this area.
Topics & Concepts
ChemistryCarbeneCatalysisMedicinal chemistryOrganic chemistryCombinatorial chemistryFluorine in Organic ChemistryN-Heterocyclic Carbenes in Organic and Inorganic ChemistrySynthesis and Reactions of Organic Compounds