Role of Thigh Muscle Changes in Knee Osteoarthritis Outcomes: Osteoarthritis Initiative Data
Bahram Mohajer, Mahsa Dolatshahi, Kamyar Moradi, Nima Najafzadeh, John Eng, Bashir Zikria, Mei Wan, Xu Cao, Frank W. Roemer, Ali Guermazi, Shadpour Demehri
Abstract
< .001). Conclusion Knee osteoarthritis was associated with longitudinal MRI-derived decreased quadriceps cross-sectional area and increased intramuscular adipose tissue. These potentially modifiable risk factors were predictive of downstream symptom worsening and knee replacement. Clinical trial registration no. NCT00080171 © RSNA, 2022
Topics & Concepts
MedicineOsteoarthritisThighConfoundingLongitudinal studyProportional hazards modelProspective cohort studyPhysical therapyInternal medicineSurgeryPathologyAlternative medicineOsteoarthritis Treatment and MechanismsLower Extremity Biomechanics and PathologiesBone and Joint Diseases