Combinatorial targeting of telomerase and DNA-PK induces synergistic apoptotic effects against Pre-B acute lymphoblastic leukemia cells
Maryam Katoueezadeh, Parisa Maleki, Seyedeh Atekeh Torabizadeh, Alireza Farsinejad, Roohollah Mirzaee Khalilabadi, Hajar Mardani Valandani, Ismaila Olanrewaju Nurain, Muhammad Hossein Ashoub, Ahmad Fatemi
Topics & Concepts
TelomeraseApoptosisFlow cytometryMolecular biologyViability assayMTT assayChemistryDNA damageDownregulation and upregulationCancer researchDNABiologyGeneBiochemistryTelomeres, Telomerase, and SenescenceCell death mechanisms and regulationDNA Repair Mechanisms