Stereoselective construction of β-, γ- and δ-lactam rings via enzymatic C–H amidation
Satyajit Roy, David A. Vargas, Pengchen Ma, Arkajyoti Sengupta, Ledong Zhu, K. N. Houk, Rudi Fasan
Topics & Concepts
ChemistryCombinatorial chemistryIntramolecular forceRegioselectivityLactamIndolizidineNitreneStereoselectivityStereochemistryPharmacophoreNatural productEnantioselective synthesisMoleculeOrganic chemistryAlkaloidCatalysisSynthesis and Catalytic ReactionsCyclopropane Reaction MechanismsCatalytic C–H Functionalization Methods