mTORC1-Dependent and GSDMD-Mediated Pyroptosis in Developmental Sevoflurane Neurotoxicity
Wenyuan Wang, Yi Wan-Qing, Hu Qi-Yun, Yu-Si Liu, Shaojie Qian, Liu Jin-Tao, Mao Hui, Cai Fang, Yang Hui-Ling
Topics & Concepts
PyroptosisSevofluranePI3K/AKT/mTOR pathwayNeurotoxicitymTORC1Programmed cell deathmTORC2Cell biologyNeuroscienceChemistryPharmacologyBiologySignal transductionApoptosisBiochemistryToxicityOrganic chemistryAnesthesia and Neurotoxicity ResearchInflammasome and immune disordersIntensive Care Unit Cognitive Disorders