Targeted nanopore sequencing with Cas9-guided adapter ligation
Timothy Gilpatrick, Isac Lee, James E. Graham, Etienne Raimondeau, Rebecca Bowen, Andrew Heron, Bradley M. Downs, Saraswati Sukumar, Fritz J. Sedlazeck, Winston Timp
Topics & Concepts
Nanopore sequencingMinionDNA sequencingAdapter (computing)Cas9BiologyDeep sequencingCRISPRComputational biologyDNA methylationNanoporeDNA sequencerGeneticsDNAGenomeGeneComputer scienceMaterials scienceGene expressionNanotechnologyOperating systemAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringCancer Genomics and Diagnostics