Multifunctional Hydrogel Electronics for Synergistic Therapy and Visual Monitoring in Wound Healing
Yun-Liang Ji, Yizhou Zhang, Jingqi Lu, Fan Gao, Xinyi Lv, Xinyu Qu, Guoyin Zhu, Tian Tian, Huan Pang, Yu Tian, Xiaochen Dong
Abstract
@C photonic crystal hydrogel is developed. This platform combines optical/electrical sensing, synergistic therapy, and real-time visual monitoring into a single, efficient system, offering a comprehensive solution for wound healing. Under photothermal stimulation, the hydrogel releases metal ions that generate hydroxyl radicals, effectively eliminating antibiotic-resistant bacteria. Beyond its antibacterial efficacy, this system offers unprecedented real-time monitoring through temperature-responsive visualization, while structural color changes upon wound exudate absorption provide a clear indication for dressing replacement. By integrating these functionalities, MHE platform allows for precise control of the therapeutic process, significantly improving wound healing and treatment monitoring. The platform's optical/electrical sensing capabilities further broaden its potential applications across other biomedical fields. This breakthrough technology provides clinicians with a powerful tool to optimize therapeutic outcomes, marking a major advancement in wound care and biomedical applications.