LncRNA GUSBP5-AS promotes EPC migration and angiogenesis and deep vein thrombosis resolution by regulating FGF2 and MMP2/9 through the miR-223-3p/FOXO1/Akt pathway
Lili Sun, Fengrui Lei, Xudong Jiang, Xiaolong Du, Lun Xiao, Wendong Li, Xiaoqiang Li
Abstract
/FOXO1/Akt pathway, which may provide a new direction for the development of DVT therapeutics.
Topics & Concepts
AngiogenesisMMP2Protein kinase BCancer researchFOXO1MedicineFibroblast growth factorGene knockdownDownregulation and upregulationSignal transductionCell biologyImmunologyBiologyInternal medicineApoptosisCancerMetastasisReceptorBiochemistryGeneCancer-related molecular mechanisms researchVenous Thromboembolism Diagnosis and ManagementLipid metabolism and disorders