Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes
C. Alexander Boecker, Juliet Goldsmith, Dan Dou, Gregory G. Cajka, Erika L.F. Holzbaur
Topics & Concepts
BiologyAutophagyLRRK2Axoplasmic transportCell biologyKinaseNeuroscienceBiochemistryApoptosisMutationGeneParkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and TherapyNerve injury and regeneration