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Universal allogeneic CAR T cells engineered with Sleeping Beauty transposons and CRISPR-CAS9 for cancer immunotherapy

Jaitip Tipanee, Ermira Samara-Kuko, Thierry Gevaert, Marinee Chuah, Thierry VandenDriessche

2022Molecular Therapy79 citationsDOIOpen Access PDF

Topics & Concepts

CRISPRTransposable elementCancer immunotherapyImmunotherapySleeping Beauty transposon systemCancerBiologyCancer researchGenomeGeneticsGeneCAR-T cell therapy researchVirus-based gene therapy researchNanowire Synthesis and Applications
Universal allogeneic CAR T cells engineered with Sleeping Beauty transposons and CRISPR-CAS9 for cancer immunotherapy | Litcius