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A divergent construction of fused and bridged carbo-/heterocyclic scaffolds<i>via</i>cascade reactions of aryl azomethine imines with vinyl cyclic carbonates

Xinyuan Cai, Xia Song, Xueying Yang, Xinying Zhang, Xuesen Fan

2023Organic Chemistry Frontiers24 citationsDOI

Abstract

Presented herein is a divergent synthesis of indene-fused pyrazoles and bridged benzodiazepines tethered with a hydroxymethyl group through the cascade reactions of aryl azomethine imines with vinyl cyclic carbonates.

Topics & Concepts

ChemistryArylHydroxymethylIndeneCascadeCombinatorial chemistryPolymer chemistryOrganic chemistryChromatographyAlkylCatalytic C–H Functionalization MethodsCyclopropane Reaction MechanismsSynthesis and Catalytic Reactions
A divergent construction of fused and bridged carbo-/heterocyclic scaffolds<i>via</i>cascade reactions of aryl azomethine imines with vinyl cyclic carbonates | Litcius