A cis-acting mechanism mediates transcriptional memory at Polycomb target genes in mammals
Daniel Holoch, Michel Wassef, Cecilia Lövkvist, Dina Zielinski, Setareh Aflaki, Bérangère Lombard, Tiphaine Héry, Damarys Loew, Martin Howard, Raphaël Margueron
Topics & Concepts
BiologyEpigeneticsPolycomb-group proteinsChromatinHistoneGeneticsRegulation of gene expressionTranscriptional regulationCell biologyGene silencingGeneTranscription factorTranscription (linguistics)RepressorPhilosophyLinguisticsGenomics and Chromatin DynamicsEpigenetics and DNA MethylationCRISPR and Genetic Engineering