Litcius/Paper detail

Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease

Jessica L. Centa, Francine M. Jodelka, Anthony J. Hinrich, Tyler B. Johnson, Joseph Ochaba, Michaela Jackson, Dominik M. Duelli, Jill M. Weimer, Frank Rigo, Michelle L. Hastings

2020Nature Medicine53 citationsDOIOpen Access PDF

Topics & Concepts

Batten diseaseExonExon skippingLysosomal storage diseaseDiseaseAntisense therapyBiologyMedicineOligonucleotideCancer researchGeneticsInternal medicineGeneAlternative splicingLocked nucleic acidLysosomal Storage Disorders ResearchCalcium signaling and nucleotide metabolismNeurogenetic and Muscular Disorders Research