Litcius/Paper detail

A comprehensive review of BET-targeting PROTACs for cancer therapy

Xiaoli Zhou, Fang Zhao, Yong-Tao Xu, Yuanyuan Guan, Tong Yu, Yizhe Zhang, Ying‐Chao Duan, Yuan Zhao

2022Bioorganic & Medicinal Chemistry39 citationsDOIOpen Access PDF

Topics & Concepts

BromodomainDrug discoveryChemistryAutophagyCancerCancer therapyBET inhibitorComputational biologyCancer researchEpigeneticsBiochemistryBiologyGeneticsApoptosisGeneProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsUbiquitin and proteasome pathways