Simultaneous tracking of autophagy and oxidative stress during stroke with an ICT-TBET integrated ratiometric two-photon platform
Wei Hu, Taotao Qiang, Li Chai, Tianyu Liang, Longfang Ren, Fei Cheng, Chunya Li, Tony D. James
Abstract
, causing cellular oxidative stress and cellular autophagy after 15 min, as such Mito-ONOO exhibits the potential for the monitoring and diagnosis of stroke, as well as providing insight into potential treatments, and drug design.
Topics & Concepts
PeroxynitriteOxidative stressFluorescenceChemistryTwo-photon excitation microscopyBiophysicsOxidative phosphorylationMitochondrionReactive oxygen speciesPhotochemistryBiochemistryBiologyOpticsPhysicsEnzymeSuperoxideElectrochemical sensors and biosensorsAnalytical Chemistry and SensorsElectrochemical Analysis and Applications