Cholinesterase activity as a potential biomarker for neurotoxicity induced by pesticides <i>in vivo</i> exposed <i>Oreochromis niloticus</i> (Nile tilapia): assessment tool for organophosphates and synthetic pyrethroids
Muhammad Amin, Masarrat Yousuf, Mohammad Attaullah, Naveed Ahmad, Mohamad Nor Azra, Mehreen Lateef, Islam Dad Buneri, Ivar Zekker, Gaber El‐Saber Batiha, Salma Mostafa Aboelenin, Muhammad Zahoor, Muhammad Ikram, Muhammad Naeem
Abstract
< 0.05) at 24 h and decreased at 48 h (except for the chlorpyrifos-treated brain and gills while tissues had shown no activity at 48 h's exposure) in all pesticides-treated tissues. The maximum increase in the activity and inhibition in the AChE activity were recorded as +92% and -52% in the chlorpyrifos and the lambda-cyhalothrin exposed brain tissues, respectively. Thus, the alterations in the AChE activities indicated that the applied pesticides are highly neurotoxic to fish and the enzyme (AChE) could be used as a useful biomarker for estimation of water pollution.