Lab-on-chip technologies for exploring the gut–immune axis in metabolic disease
Alexandra Wheeler, Verena Stoeger, Róisı́n M. Owens
Abstract
-like immune cell dynamics as well as host-microbiome interactions are limited. Future model development should focus on combining these conditions to create an environment capable of hosting more complex microbiota and immune cells to allow further study into the effects of diet and related metabolites on the gut-immune ecosystem and their role in the prevention and development of metabolic diseases in humans.
Topics & Concepts
Immune systemChipDiseaseBiologyEngineeringImmunologyMedicineInternal medicineTelecommunications3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis ApplicationsGut microbiota and health