The protective effect of betanin and copper on spinal cord ischemia–reperfusion injury
Kevser Tural, Özkan Özden, Zeynep Bilgi, Emre Kubat, Celal Şahin Ermutlu, Oğuz MERHAN, İrfan Taşoğlu
Abstract
I/R injury of the spinal cord can be successfully demonstrated by aortic clamping in this surgical model. Betanin/Copper sulphate has ameliorative effects against operative I/R injury. Low toxicity of those agents makes them ideal targets for clinical research for this purpose.
Topics & Concepts
MalondialdehydeMedicinePharmacologyBetaninTUNEL assaySuperoxide dismutaseLaparotomyReperfusion injuryAnesthesiaIschemiaApoptosisChemistryOxidative stressEndocrinologyInternal medicineBiochemistryAntioxidantSurgeryBotanical Research and ApplicationsCassava research and cyanideChemical synthesis and alkaloids