Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action
Lance A. Thielen, Junqin Chen, Jing Gu, Omar Moukha‐Chafiq, Guanlan Xu, SEONGHO JO, Truman Grayson, Brian Lu, Peng Li, Corinne E. Augelli‐Szafran, Mark J. Suto, Matt Kanke, Praveen Sethupathy, Jason K. Kim, Anath Shalev
Topics & Concepts
TXNIPIdentification (biology)Action (physics)Diabetes mellitusGlucagon-like peptide-1GlucagonPharmacologyMedicineSmall moleculeChemistryComputational biologyEndocrinologyBiologyBiochemistryInsulinType 2 diabetesPhysicsBotanyThioredoxinOxidative stressQuantum mechanicsPeptidase Inhibition and AnalysisDiabetes Treatment and ManagementUbiquitin and proteasome pathways