Approved and investigational fluorescent optical imaging agents for disease detection in surgery
Sonia Rehman, Paul M. Brennan, Annamaria Lilienkampf, Mark Bradley
Abstract
Fluorescent optical imaging is becoming an increasingly attractive imaging tool that physicians can utilise as it can detect previously 'unseen' changes in tissue at a cellular level that are consistent with disease. This is possible using a range of fluorescently labelled imaging agents that, once excited by specific wavelengths of light, can illuminate damaged and diseased tissues. For surgeons, such agents can permit dynamic, intraoperative imaging providing a real-time guide as they resect diseased tissue.
Topics & Concepts
MedicineOptical imagingFluorescenceFluorescence-lifetime imaging microscopyPathologyBiomedical engineeringRadiologyMedical physicsOpticsPhysicsNanoplatforms for cancer theranosticsCancer Research and TreatmentsCancer, Hypoxia, and Metabolism