A GSH-depleted platinum(IV) prodrug triggers ferroptotic cell death in breast cancer
Dachuan Qi, Lei Xing, Lijun Shen, Wenshuang Sun, Cheng Cai, Chunhua Xue, Xuwei Song, Hua Yu, Hu‐Lin Jiang, Chengjun Li, Qing‐Ri Jin, Zhiqi Zhang
Topics & Concepts
CisplatinProdrugChemistryGlutathioneProgrammed cell deathApoptosisCancer researchOxidative stressPharmacologyCancer cellBreast cancerFree radical scavengerCancerBiochemistryMedicineChemotherapyInternal medicineEnzymeFerroptosis and cancer prognosisFerrocene Chemistry and ApplicationsMicroRNA in disease regulation