Adult neural stem cells have latent inflammatory potential that is kept suppressed by <i>Tcf4</i> to facilitate adult neurogenesis
Mohammad Shariq, Vinaya Sahasrabuddhe, Sreevatsan Krishna, Swathi Radha, Nruthyathi, Ravishankara Bellampalli, Anukriti Dwivedi, Rajit Narayanan Cheramangalam, Boris Reizis, Jean M. Hébert, Hiyaa S. Ghosh
Abstract
as a critical regulator that facilitates adult neurogenesis via proactive suppression of this detrimental potential.
Topics & Concepts
NeurogenesisNeural stem cellTCF4Stem cellAdult stem cellNeuroscienceBiologyMedicineGeneCellular differentiationCell biologyGene expressionGeneticsPromoterNeurogenesis and neuroplasticity mechanismsNeuroinflammation and Neurodegeneration MechanismsGenetics and Neurodevelopmental Disorders