Development of a zinc(<scp>ii</scp>) 2-pyridinecarboxaldehyde thiosemicarbazone complex with remarkable antitumor and antiangiogenic activities
Ming Jiang, Jinhui Pang, Xiaoying Jia, Yong Chu, Wenjuan Li, Hong Liang, Feng Yang
Abstract
. We further confirmed the antitumor mechanisms of C5, including arresting the cell cycle at the S phase, inducing apoptosis, inducing lethal autophagy, and suppressing angiogenesis.
Topics & Concepts
SemicarbazoneZincChemistryCell biologyStereochemistryBiologyOrganic chemistryMetal complexes synthesis and propertiesLanthanide and Transition Metal ComplexesMagnetism in coordination complexes