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Ruthenium-Catalyzed Hydrogen Evolution <i>o</i>-Aminoalkylation of Phenols with Cyclic Amines

Liang Cao, He Zhao, Zhenda Tan, Rongqing Guan, Huanfeng Jiang, Min Zhang

2020Organic Letters25 citationsDOI

Abstract

-aminoalkylation of phenolic derivatives with cyclic amines as the coupling agents. The developed cross-coupling reaction offers a practical platform for direct access to a variety of functionalized phenols with the features of good substrate and functional group compatibility, readily available catalyst system and feedstocks, no need for additional sacrificial oxidants, and high atom efficiency.

Topics & Concepts

RutheniumChemistryCatalysisPhenolsCyclic aminesCombinatorial chemistryHydrogenFunctional groupCompatibility (geochemistry)Substrate (aquarium)Atom economyOrganic chemistryChemical engineeringPolymerGeologyEngineeringOceanographyAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization MethodsCarbon dioxide utilization in catalysis
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