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Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy

Chaitali Misra, Sushant Bangru, Feikai Lin, Kin Lam, Sara N. Koenig, Ellen R. Lubbers, Jamila Hedhli, Nathaniel P. Murphy, Darren J. Parker, Lawrence W. Dobrucki, Thomas A. Cooper, Emad Tajkhorshid, Peter J. Mohler, Auinash Kalsotra

2020Developmental Cell50 citationsDOIOpen Access PDF

Topics & Concepts

Myotonic dystrophyBiologyGene isoformAlternative splicingDownregulation and upregulationRNA splicingUntranslated regionCell biologyCardiac muscleTranscriptomemicroRNAMyocyteRNA-binding proteinThree prime untranslated regionGeneticsMessenger RNAGene expressionMolecular biologyGeneRNAEndocrinologyGenetic Neurodegenerative DiseasesRNA Research and SplicingMitochondrial Function and Pathology
Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy | Litcius