Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells
Kunhua Qin, Peng Huang, Ruopeng Feng, Cheryl A. Keller, Scott A. Peslak, Eugene Khandros, Megan S. Saari, Xianjiang Lan, Thiyagaraj Mayuranathan, Phillip A. Doerfler, Osheiza Abdulmalik, Belinda Giardine, Stella T. Chou, Junwei Shi, Ross C. Hardison, Mitchell J. Weiss, Gerd A. Blobel
Topics & Concepts
BiologyGene silencingFetal hemoglobinGlobinGeneGeneticsCRISPRTranscription factorCell biologyMolecular biologyFetusPregnancyHemoglobinopathies and Related DisordersEpigenetics and DNA MethylationIron Metabolism and Disorders