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Variability of voriconazole concentrations in patients with hematopoietic stem cell transplantation and hematological malignancies: influence of loading dose, procalcitonin, and pregnane X receptor polymorphisms

Guangting Zeng, Linlin Wang, Lihong Shi, Huilan Li, Miaomiao Zhu, Jia Luo, Zanling Zhang

2020European Journal of Clinical Pharmacology35 citationsDOI

Topics & Concepts

VoriconazolePregnane X receptorHematopoietic stem cell transplantationProcalcitoninTransplantationMedicineStem cellHaematopoiesisInternal medicinePharmacologyOncologyBiologyImmunologyNuclear receptorGeneticsSepsisAntifungalGeneDermatologyTranscription factorAntifungal resistance and susceptibilityNeutrophil, Myeloperoxidase and Oxidative MechanismsNeutropenia and Cancer Infections
Variability of voriconazole concentrations in patients with hematopoietic stem cell transplantation and hematological malignancies: influence of loading dose, procalcitonin, and pregnane X receptor polymorphisms | Litcius