Tannic acid-reinforced zwitterionic hydrogels with multi-functionalities for diabetic wound treatment
Kun Fang, Qinwei Gu, Mingzhu Zeng, Zhimao Huang, Haofeng Qiu, Jiru Miao, Yue Fang, Yinyu Zhao, Ying Xiao, Ting Xu, Robert Petrovich Golodok, Vadim Victorovich Savich, Alexander Phyodorovich Ilyushchenko, Fanrong Ai, Donglei Liu, Rong Wang
Abstract
studies confirmed that the hydrogel has good cytocompatibility and negligible skin irritation, and promoted healing of diabetic wounds in mice. Such tough and effective hydrogel with a straightforward preparation strategy holds great promise as wound dressings for diabetic wound treatment.
Topics & Concepts
Tannic acidSelf-healing hydrogelsMaterials scienceUltimate tensile strengthWound healingIn vivoDiabetic footMethacrylateCompressive strengthAdhesionSkin repairComposite materialBiomedical engineeringChemistrySurgeryPolymer chemistryCopolymerDiabetes mellitusMedicinePolymerOrganic chemistryBiologyBiotechnologyEndocrinologyWound Healing and TreatmentsDiabetic Foot Ulcer Assessment and ManagementPressure Ulcer Prevention and Management