Shared structural mechanisms of general anaesthetics and benzodiazepines
Jeong Joo Kim, Anant Gharpure, Jinfeng Teng, Yuxuan Zhuang, Rebecca J. Howard, Shaotong Zhu, Colleen Noviello, Richard M. Walsh, Erik Lindahl, Ryan Hibbs
Topics & Concepts
GABAA receptorAllosteric regulationFlumazenilBenzodiazepineChemistryEtomidateReceptorFlunitrazepamPharmacologyGABAA-rho receptorInhibitory postsynaptic potentialBiophysicsNeurosciencePropofolBiochemistryMedicineBiologyNeuroscience and Neuropharmacology ResearchPhotoreceptor and optogenetics researchLipid Membrane Structure and Behavior