MRI-based Zero Echo Time and Black Bone Pseudo-CT Compared with Whole-Body CT to Detect Osteolytic Lesions in Multiple Myeloma
Frédéric Lecouvet, Deniz Zan, Darius Lepot, Caroline Chabot, Marie‐Christiane Vekemans, Gaëtan Duchêne, Ophélye Chiabai, Perrine Triqueneaux, Thomas Kirchgesner, Lokmane Taihi, Julie Poujol, Olivier Gheysens, Nicolas Michoux
Abstract
< .021). Regardless of the sequence or region, repeatability was very good (AC1 ≥0.87 for all), while reproducibility was at least good (AC2 ≥0.63 for all). Conclusion Both MRI-based ZTE and BB pseudo-CT sequences of the lumbar spine, pelvis, and femurs demonstrated high diagnostic accuracy in detecting osteolytic lesions in MM. Compared with BB, the ZTE sequence yielded more FN findings in the spine. ClinicalTrials.gov Identifier: NCT05381077 Published under a CC BY 4.0 license.
Topics & Concepts
MedicineMultiple myelomaNuclear medicineEcho (communications protocol)RadiologyEcho timeMagnetic resonance imagingInternal medicineComputer networkComputer scienceMultiple Myeloma Research and TreatmentsBone health and treatmentsBone Tumor Diagnosis and Treatments