Litcius/Paper detail

Surface enhanced Raman scattering for the multiplexed detection of pathogenic microorganisms: towards point-of-use applications

M. Berry, Hayleigh Kearns, Duncan Graham, Karen Faulds

2021The Analyst48 citationsDOIOpen Access PDF

Abstract

Surface enhanced Raman scattering (SERS) is a technique that demonstrates a number of advantages for the rapid, specific and sensitive detection of pathogenic microorganisms. In this review, an overview of label-free and label-based SERS approaches, including microfluidics, nucleic acid detection and immunoassays, for the multiplexed detection of pathogenic bacteria and viruses from the last decade will be discussed, as well as their transition into promising point-of-use detection technologies in industrial and medical settings.

Topics & Concepts

Raman scatteringNanotechnologyMicrofluidicsMultiplexingPathogenic bacteriaNucleic acidMicroorganismNucleic acid detectionDetection limitMaterials scienceRaman spectroscopyChemistryBacteriaComputer scienceBiologyPhysicsOpticsChromatographyBiochemistryGeneticsTelecommunicationsBiosensors and Analytical DetectionSARS-CoV-2 detection and testingAdvanced biosensing and bioanalysis techniques