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Dietary inflammatory index and its relation to the pathophysiological aspects of obesity: a narrative review

Roseli Neves de Mello, Bárbara Paixão de Gois, Ana Claudia Pelissari Kravchychyn, Ana Raimunda Dâmaso, Maria Aderuza Horst, Gláucia Carielo Lima, Flávia Campos Corgosinho

2023Archives of Endocrinology and Metabolism16 citationsDOIOpen Access PDF

Abstract

), a literature-derived dietary index, was developed in 2009 to characterize the inflammatory potential of a habitual diet. Abundant research has been conducted to investigate the associations between DII and obesity. In this narrative review, we examined the current state of the science regarding the relationships between DII and the inflammatory pathophysiological aspects related to obesity. DII is associated with inflammation in obesity. The most pro-inflammatory diet was directly related to higher levels of pro-inflammatory markers, which included C-reactive protein (CRP), interleukin-6 (IL-6), IL-1β, and tumor necrosis factor-α (TNF-α). Therefore, evidence suggests that the use of the DII may be useful for understanding the relationship between diet and the inflammatory process related to obesity.

Topics & Concepts

MedicineInflammationObesityPathophysiologyPathogenesisTumor necrosis factor alphaImmunologyDiseaseNarrative reviewBody mass indexBioinformaticsInternal medicineIntensive care medicineBiologyNutritional Studies and DietDiet and metabolism studiesAdipokines, Inflammation, and Metabolic Diseases
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