Synthesis and evaluation of stereoisomers of methylated catechin and epigallocatechin derivatives on modulating P-glycoprotein-mediated multidrug resistance in cancers
Iris L. K. Wong, Xing-kai Wang, Zhen Liu, Wenqin Sun, Fu-xing Li, Bao-Chao Wang, Peng Li, Shengbiao Wan, Larry M. C. Chow
Topics & Concepts
ChemistryP-glycoproteinEffluxMultiple drug resistanceCatechinLinkerIC50CytotoxicityAbcg2StereochemistryPharmacologyIn vitroBiochemistryATP-binding cassette transporterPolyphenolTransporterAntioxidantGeneBiologyComputer scienceAntibioticsOperating systemDrug Transport and Resistance MechanismsNanoparticle-Based Drug DeliveryTea Polyphenols and Effects